Description
Product Characteristics: AR1, SPBP, Stromelysin-1 Platelet-Derived Growth Factor-Responsive Element Binding Protein, Stromelysin-1 PDGF-responsive element-binding protein, SPRE-binding protein
Target Information: The protein encoded by this gene binds a platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 (stromelysin 1) promoter. The protein localizes to the nucleus and displays DNA-binding and transactivation activities. It is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]